WARD-glucose validation

Official title:

Validation of the Accuracy of Continuous Glucose Monitoring Using the Dexcom G7 in Patients With Diabetes in Situations With Circulatory Impairment. A Prospective Observational Study

Study design:

Prospective observational cohort

Sample size:

60 participants

Study Sites:

Rigshospitalet and Bispebjerg Hospital

Inclusion criteria:

Adult patients with diabetes mellitus who a) undergo surgery lasting >45 minutes or b) are admitted to the intensive care unit (ICU) with circulatory impairment (requiring continuous infusion of vasopressors and a reduced peripheral perfusion).

Study Procedures:

Included patients will wear a continuous glucose monitoring (CGM) device (Dexcom G7) during the stay at the hospital (up to 10 days). Through a sensor placed subcutaneously, the Dexcom G7 measures glucose levels every 5 minutes and transmit readings this to a receiver at the patient bed. The glucose readings will be blinded to the patients and nursing staff. Thus, the patients’ glucose levels will be monitored through standard practice with point-of-care (POC) blood glucose measurements. After the study period, the accuracy of CGM readings will be assessed by comparing these to POC blood glucose measurements

Outcome:

The primary outcome is the accuracy of the CGM device compared to standard POC blood glucose measurements.

Primary Investigators:

Casper Pedersen, MD PhD student

NCT:

NCT06297850